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Filtered Search Results
Medchemexpress LLC Suzetrigine phenol | 2649467-91-2 | 99.4% | 459.37 | 1 MG
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Suzetrigine phenol is the phenolate form of the sodium channel modulator Suzetrigine. It is an orally active and highly selective inhibitor of NaV1.8.
- Phenolate form of Suzetrigine
- Orally active and highly selective inhibitor of NaV1.8
- For research use only
- Modulates sodium channels
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Medchemexpress LLC Pentanoic acid, 2-[(2S,4S)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-[ | 56124-62-0 | MFCD01939322 | 99.6% | C34H36F3NO13 | 10MG
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Valrubicin is an anthracycline chemotherapy agent provided for research use. It inhibits TPA- and PDBu-induced protein kinase C (PKC) activation with reported IC50 values of 0.85 μM and 1.25 μM, and demonstrates antitumor and anti-inflammatory activity in preclinical studies.
- Inhibits TPA- and PDBu-induced protein kinase C activation (IC50 0.85 μM and 1.25 μM).
- Exhibits antitumor and anti-inflammatory activity in preclinical models.
- Provided as a research-grade small molecule for biochemical and cellular assays.
- High purity suitable for analytical applications (purity 99.6% by LCMS).
- Available in small pack sizes suitable for assay development and reference standards.
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Medchemexpress LLC Zalunfiban dihydrochloride | 2815778-41-5 | 99.1% | 10 MG
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Zalunfiban dihydrochloride is a potent, selective platelet αIIbβ3 antagonist (IC50 45 nM) supplied as a high-purity solid for in vitro and in vivo research on platelet function and myocardial infarction.
- CAS number: 2815778-41-5
- Molecular formula: C16H20Cl2N8O2S
- Molecular weight: 459.35 g/mol
- Purity: 99.1%
- Appearance: Solid
- In vitro solubility: DMSO 10 mg/mL (21.77 mM) with sonication and warming
- Suggested storage: 4°C sealed, away from moisture; in solvent -80°C (6 months)
- Typical pack size: 10 mg
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Cayman Chemical Phenol-13C6 500mg
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A building block; has been used in the synthesis of 13C6-labeled metabolites of (±)-asenapine
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Medchemexpress LLC HY-N0828 25mg Medchemexpress, Pterostilbene CAS:537-42-8 Purity:>98%
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Medchemexpress, HY-N0828 25mg Pterostilbene CAS:537-42-8 Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium [1] . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties [1] [4] . Pterostilbene blocks ROS production [3] , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide [4] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Dy131 (GSK 9089) | 95167-41-2 | C18H21N3O2 | 5 MG
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DY131 (GSK 9089) is a potent and selective ERRγ and ERRβ agonist. It is inactive against ERRα, ERα, and ERβ, and also inhibits Smo signaling.
- Potent and selective ERRγ and ERRβ agonist
- Inactive against ERRα, ERα, and ERβ
- Inhibits smo signaling
- Suppresses cell proliferation in LNCaP-ERRγ and LNCaP cells
- Inhibits Shh induced accumulation of Smo::EGFP
- Decreases phosphorylated histone H3 (pH3) marked proliferation of CGNPs
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Medchemexpress LLC Plicamycin (Mithramycin A) | 18378-89-7 | MFCD00135618 | 99.46% | C52H76O24 | 50 MG
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Plicamycin (Mithramycin A) is a selective specificity protein 1 (Sp1) inhibitor that inhibits the growth of various cancers by decreasing Sp1 protein. It also inhibits GSTM2 promoter activity and protein expression. It has demonstrated antitumorigenic activity in xenograft models, reducing tumor volume and weight with minimal toxicity.
- Selective specificity protein 1 (Sp1) inhibitor
- Inhibits growth of various cancers by decreasing Sp1 protein
- Inhibits GSTM2 promoter activity and protein expression
- Induces proteasome-dependent degradation of Sp1 protein
- Suppresses cervical cancer growth via a DR5/caspase-8/Bid signaling pathway
- Demonstrates concentration-dependent inhibition of HEp-2 and KB cell growth
- Causes significant DNA fragmentation
- Antitumorigenic activity in xenograft models
- Reduces tumor volume and weight with minimal toxicity
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eMolecules 1448706-36-2 | ChemScene | (2R4S)-Benzyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate | 100mg | 536862709 | CS-W020199 | MFCD09998723 | 251.282 | C13H17NO4
ChemScene | 2-(Boc-amino)pyridine-5-carboxaldehyde | 100mg | 654744493 | CS-0130480 | 199296-40-7 | MFCD08064228 | 222.244 | C11H14N2O3
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Medchemexpress LLC HY-100489 1g Medchemexpress, TBHQ tert-Butylhydroquinone CAS:1948-33-0 Purity:98%
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Medchemexpress,HY-100489 1g TBHQ tert-Butylhydroquinone CAS:1948-33-0 Formula:C10H14O2 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-112822 10mg Medchemexpress, ON-013100 CAS:865783-95-5 Purity:>98%
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Medchemexpress, HY-112822 10mg ON-013100 CAS:865783-95-5 ON-013100, an antineoplastic drug, acts a mitotic inhibitor that could inhibit Cyclin D1 expression. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC RKI-1447 dihydrochloride | 1782109-09-4 | 99.9% | 399.29 | 100 MG
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RKI-1447 dihydrochloride is a potent and selective ROCK inhibitor with IC50s of 14.5 and 6.2 nM for ROCK1 and ROCK2, respectively. It suppresses colorectal carcinoma cell growth and promotes apoptosis.
- Potent and selective ROCK inhibitor
- Suppresses colorectal carcinoma cell growth
- Promotes apoptosis
- Suppresses phosphorylation of the ROCK substrates MLC-2 and MYPT-1 in human cancer cells
- Exhibits effective anticancer activity in colorectal carcinoma (CRC)
- Inhibits mammary tumor growth in vivo
- Does not exert physiological toxicity on mice in vivo
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Medchemexpress LLC Honokiol dichloroacetate | 1620160-42-0 | 99.1% | 488.19 g/mol | C22H18Cl4O4 | 10MG
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Honokiol DCA (honokiol dichloroacetate) is a dichloroacetate analog of honokiol supplied for research use. It has been reported to inhibit growth of human prostate cancer cells in vitro and to suppress androgen receptor (AR) protein levels, and is commonly used in cellular and mechanistic studies.
- Dichloroacetate analog of honokiol.
- Reported to inhibit prostate cancer cell growth in vitro.
- Suppresses androgen receptor protein levels.
- Available as mg-scale solids and as 10 mM solution in DMSO.
- High purity (about 99.1%).
- Molecular weight 488.19 g/mol; formula C22H18Cl4O4.
- For research use only; not for clinical use.
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Alkali Scientific LB Broth [Lennox] Powder, 2 Kg
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LB Broth (Lennox) Powder, 10kg, is designed for high-volume applications in microbiology and molecular biology labs. This high-performance medium supports the growth of a wide range of bacterial species, particularly Escherichia coli, which is commonly used in genetic engineering and cloning studies. The Lennox formulation offers a balanced nutrient profile that ensures optimal bacterial growth while maintaining the simplicity and cost-effectiveness of standard LB media. This medium is widely used in recombinant DNA research, protein expression, and general bacterial culture for laboratory applications. The powder form provides flexibility and convenience in large-scale preparations.
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Medchemexpress LLC ML-109 | 1186649-91-1 | 99.02% | 523.58 | 100 MG
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ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM. It is for research use only.
- Potent and full agonist at TSHR with an EC50 of 40 nM.
- No activity at FSHR or LHCGR.
- Surprisingly stable under neutral and basic conditions (t1/2 of ~16 h), though it degrades at low pH (t1/2 of ~3 h).
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eMolecules 5786-54-9 | Medchem Express | Hispidol | 5mg | 446257621 | HY-102040 | MFCD00135406 | 254.241 | C15H10O4
Medchem Express | Hispidol | 5mg | 446257621 | HY-102040 | 5786-54-9 | MFCD00135406 | 254.241 | C15H10O4
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